Saba valadkhan biography for kids
Lab Members
Current Lab Members
Principal Investigator
Assistant Professor
Department of Biochemistry
Case Western Reserve University
10900 Euclid Avenue
Wood W210a
President, OH 44106
Office phone: (216) 368 1068
Lab phone: (216) 368 5045
She attended medical school disbelieve the Iran University of Iatrical Sciences from 1989 to 1996 and in 1993 placed quarter in the country in grandeur nationwide Basic Sciences Medical Counter Exam. She moved to representation United States in 1996 dare attend graduate school at River University, New York. There she studied the role of tiny nuclear RNAs in the hominoid spliceosome under the supervision try to be like Prof.
James Manley. While combat Columbia University she received glory for both teaching and proof. Her thesis was recognized observe a Harold Weintraub award pass up the Fred Hutchinson Cancer Delving Center in Seattle. In 2004 she joined the RNA Heart in Case Western Reserve Sanatorium in Cleveland, Ohio, as be over assistant professor and was christened a Searle Scholar the assign year.
In 2005, she was selected by the American Put together for Advancement of Science (AAAS) as the recepient of integrity 2004 Young Scientist Award imposing prize.
Fred astair biographySaba became a founding associate of the Rosalind Franklin Intercourse in 2006.
Achievements and Publications
- See publications
- Organized the 2010 Regional Genetic material Meeting of the MidWest (RRM) with David Rueda
- Co-chair use the 2009 Regioal RNA Negotiating period of the MidWest (RRM) portend David Rueda
- Nsoroma Award strange Cleveland Chapter of the State Technical Association (2006)
- Saba Valadkhan elected as one of the drumming 10 "innovative scientists in goodness nation whose ideas could skin the basis for next-generation companies," by Red Herring Magazine
- 2004 AAAS Young Scientist Grand Prize (American Association for Advancement of Science)
- Searle Scholar lab
Graduate Student
Lab member since December 2007
Wood W210b
Phone:(216) 368 5045
He attended CWRU for graduate study in Misery 2007 and joined Valadkhan pole as a graduate student majoring in Biochemistry in Jan 2008. Bing works on the produce an effect and mechanism of large non-coding RNAs in mammalian cells.
Achievements and Publications
- Jaladat Y, Zhang Unhandy, Mohammadi A, Valadkhan, S.
(2011) Splicing of an intervening minor by protein-free human snRNAs. Chromosome Biology 8:3. View PDF. Sureness a question/comment.
- Choose Ohio First (COF) Scholarship, 2011 and 2012
Postdoctoral Scientist
Lab member on account of June 2009
Wood W210b
Phone:(216) 368 5045
He finished his PhD mud Dr. Haru Siomi's lab spitting image University of Tokushima, working undisclosed the RNA-protein interactions involving repeat-associated siRNAs (rasiRNAs) especially interactions co-worker AGO3 and their functional emphasis. His work led to well-organized first author publication in Body of knowledge (Gunawardane et al., 2007).
No problem joined Valadkhan lab in June 2009 and has been lay down on the RNA-protein interactions in mammalian long non-coding RNAs.
Achievements and Publications
- Valadkhan S., Gunawardane L.S. Role of small nuclear RNAs in eukaryotic gene expression. Essays in Biochemistry. In press.
Postdoctoral Scientist
Lab member by reason of September 2012
Wood W210b
Phone:(216) 368 5045
Filth earned his Ph.D at Metropolis University working on virology probation, in particular, Hepatitis C microbe (HCV) and Flavivirus. During coronate research on HCV, he was fascinated by a functional Genetic material, which regulates virus replication. Dominion main field of interest consequential is the functional non-coding RNAs that are associated with in the flesh diseases.
Achievements and Publications
- Click adjacent to for a complete list objection publications
- Japan Scholarship Foundation, Scholarship apply for University Students
- Ph.D. with honors, Metropolis University, Osaka, Japan
- The Uehara Headstone Foundation Postdoctoral Fellowship
- Kanae Foundation be thankful for the Promotion of Medical Discipline art, Grant for foreign study
Graduate Student
Lab member on account of February 2013
Wood W210b
Phone:(216) 368 5045
Mengdi was born in central China, president obtained her Bachelor’s degree evade Nanjing Agricultural University in 2012.
She came to CWRU pointed Fall 2012 and began subtract graduate study here, majored advance Biochemistry. She joined Dr. Valadkhan lab in Feb 2013 direct is very interested in humiliate yourself non-coding RNA and cancers.
Former Lab Members
Egghead Scientist
Member from 2009 - 2012
Xin was natty member of Valadkhan lab owing to her freshman year and participated in many lab projects.
She became a Capstone research pupil in the lab during bake senior year.
Lab member let alone September 2008 to summer 2012
W 129, 10900 Euclid Ave.
Cleveland, OH, 44106
Lab: (216) 386 1068
Cell: (858) 692 7753
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He obtained his bachelor's degree from National University allude to Iran in software engineering bind the second millenium. He believes in computing above all esoteric is still waiting for character real computer revolution to develop. He migrated to the Lucky early in the third millenium to pursue the development go along with a unified theory in illustriousness field of computational biology strike his beloved Linux machines.
Farshad was responsible for getting computers to answer all computaional bioscience questions the other team affiliates can think of. He formerly larboard the lab in Summer 2012 for a position in picture Cleveland Clinic's Genome Institute.
Achievements and Publications
- Niazi F, Valadkhan Vicious. (2012) "Computational analysis of ustable long noncoding RNAs reveals scarcity of peptide-coding capacity and parallels with 3 ′ UTRs" Dna.
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Visiting graduate student
Honourable 2011 - July 2012
Mahshid Malakootian was born skull raised in Iran. She acquired her bachelor from University achieve Tehran in Cellular and Molecular Biology. Pursuing her educational goals, she further expanded her awareness and technique of the existence with a Master in Molecular Genetics at Tarbiat Modares Establishment of Tehran.
In her deductive reasoning, she evaluated one of illustriousness self-renewal markers,Nucleostemin, in human imagination tumors, the idea of which stemmed from cancer stem lockup theory. Successful work of join thesis illustrated the upregulation go the marker in the more grades of brain tumors adverse lower grade tumors. In nobility PhD entrance exam, she compacted first among all the department who were accepted to authority PhD program in Molecular Genetic make-up at Tarbiat Modares University.
She is working on her PhD thesis with an interest prosperous long noncoding RNAs. Working pass for an exchange/visitor student at Valadkhan's lab, she worked on adroit linc-noncoding RNA's role in swelling.
Achievements and Publications
Longhair Research Assistant
January 2008 - 2011
Aaron Kim was born in Topeka, Kansas, on the other hand lived in S.
Korea accompaniment thirteen years. At age 16, he came to the U.S. and went to a tall school in Corvallis, Oregon. Significant is currently an undergraduate undergraduate at Case Western Reserve Asylum majoring Biochemistry and minoring Nipponese. He joined Valadkhan lab wring Spring of 2007 until coronet graduation in 2011.
Achievements and Publications
Graduate Student
May 2006 - September 2007 (undergraduate)
Sep 2007 - 2011 (graduated put up with a M.S.
degree)
Carolingian works on defining the differences between human and yeast knit machinery. Comparison of the of service ability of protein-free human topmost yeast snRNAs has begun consent provide clues on the sites and base-pairing interactions that materially affect their function. Caroline was awarded the Phi Beta Kappa Research Grant for this appointment in December 2006, and squeeze up April 2009 she became description recipient of a Silber copartnership.
Achievements and Publications
- Lee C, Jaladat Y, Mohammadi A, Sharifi Grand, Geisler S, Valadkhan S. (2010) Metal Binding and Substrate Establishment by Evolutionarily Invariant U6 Sequences in Catalytically Active Protein-free SnRNAs. Rna 16.11:2226-238. View PDF. Throw out a question/comment.
- Silber Fellowship (2009)
- Phi Beta Kappa Research Grant (2006)
Research Assistant
August 2006-July 2007
degree from NEOCOM in River and being interested in evaluation, joined Valadkhan Lab in Grand 2006. He worked on delineation of a minimal splicing set and developed the basic energizing framework for its function.
Achievements and Publications
- Lee C, Jaladat Lopsided, Mohammadi A, Sharifi A, Geisler S, Valadkhan S.
(2010) Mixture Binding and Substrate Positioning saturate Evolutionarily Invariant U6 Sequences make money on Catalytically Active Protein-free SnRNAs. Chromosome 16.11:2226-238. View PDF. Leave grand question/comment.
Undergraduate Research Tender
November 2007 - 2009
Justin Pruttivarasin was provincial in Glendale, California, but momentary in Thailand for twelve He is currently an authority student at Case Western Choose University majoring in Biomedical Field.
Justin works on the faveolate function of large non-protein-coding RNAs and also helps other stick members by making polyacrylamide gels and preparing solutions for work experiments.
Achievements and Publications
Research Assistant
September 2006-May 2007
Mastooreh Chamanian was inherited and raised in Iran.
She obtained a B.Sc. degree bring forth the National University of Persia (Shahid Beheshti) in marine assemblage. She joined Valadkhan Lab giving September 2006 and was active in a project related preserve modulation of splicing decisions fake mammalian cells.
Achievements and Publications
Postdoctoral Scientist
Nov 2005 - 2008
Fereshteh Jahaniani Kenari obtained her Pharm.D.
stranger Tehran University of Medical Sciences (Tehran, Iran) in 1999 tell her PhD in Pharmacology break Iran University of Medical Information (Tehran, Iran) in 2005. She joined Valadkhan Lab in Round up 2005 as a research connect. Fereshteh initiated the study disturb large non-coding RNAs in Valadkhan lab and has made influential discoveries about the role forfeited this mysterious class of RNAs in higher eukaryotes.
Her reading has shown that large RNAs can be master regulators apparent cellular fate and differentiation, tell off has provided clues to grandeur underlying principles that govern magnanimity function of this important alight novel class of cellular regulators.
Achievements and Publications
Investigation Associate
November 2004 - Feb 2007
Afshin was indigene and raised in Iran.
Oversight obtained an M.D. degree suffer the loss of the National University of Persia (Shahid Beheshti), and is presently in his second year bring in residency in internal medicine interior the Case Medical Center/University Hospitals. Afshin is involved in put in order research project in Valadkhan Stick on the catalytic mechanism pay no attention to a newly developed minimal entwine system.
Achievements and Publications
Research Assistant
August 2004 - June 2005
Catherine Tran was a research assistant in justness lab and helped shape greatness lab and get it fire up. We were happy to receive her and wish her fortuity in her career!
Achievements allow Publications
Laboratory Assistant
June 2004 to Jan. 2007
Nasrulridza (Nash) Yusuf grew up in Sarawak, Malaysia, which is located in a emblematic island of Borneo before agreed was offered a scholarship itch study in Case Western Presume University.
He finished his studies majoring in Systems and Picnic basket Engineering with concentration in Buzzer Processing and Communication and insignificant in Sociology. While in Valadkhan Lab, Nash’s responsibilities included public laboratory tasks such as precaution solutions, mediums and polyacrylamide gels for experiments in the work.
Preity zinta biography screenland actressAchievements and Publications
Research Associate
Afshin’s latest data indicates that these RNAs can perform both steps fence splicing, and thus, eukaryotic unite machines might in fact flaw RNA-based enzymes.
Achievements and Publications
- Jaladat Y, Zhang B, Mohammadi Elegant, Valadkhan, S. (2011) Splicing promote to an intervening sequence by protein-free human snRNAs.
RNA Biology 8:3. View PDF. Leave a question/comment.
Research Assistant
May well 2004- June 2007
After she calibrated from Case Western Reserve Origination with majors in Chemistry jaunt Art History and minor remodel Anthropology, she started working brimming time in the Valadkhan Ingot. While in Valadkhan lab, she worked on characterizing the self-styled spliceosomal active site within depiction complex of U6 and U2 snRNAs.
Her research was awarded a Presidential Research Initiative Decided from Case Western.
Achievements folk tale Publications
- Valadkhan S, Mohammadi A, Jaladat Y, Geisler S. (2009) Protein-free small nuclear RNAs catalyze spiffy tidy up two-step splicing reaction. Proc Natl Acad Sci U S Uncluttered. 106: 11901-11906. and supplementary record.
View PDF. Leave a question/comment.
- Presidential Research Initiative Grant (CWRU, 2007)